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Oncogenic BRAF(V600E) inhibits BIM expression to promote melanoma cell survival
Somatic activating mutations of BRAF are the earliest and most common genetic abnormality detected in the genesis of human melanoma. However, the mechanism(s) by which activated BRAF promotes melanoma cell cycle progression and/or survival remain unclear. Here we demonstrate that expression of BIM,...
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| Pubblicato in: | Pigment Cell Melanoma Res |
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| Autori principali: | , , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2007
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4916913/ https://ncbi.nlm.nih.gov/pubmed/18715233 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1755-148X.2008.00491.x |
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