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Oncogenic BRAF(V600E) inhibits BIM expression to promote melanoma cell survival
Somatic activating mutations of BRAF are the earliest and most common genetic abnormality detected in the genesis of human melanoma. However, the mechanism(s) by which activated BRAF promotes melanoma cell cycle progression and/or survival remain unclear. Here we demonstrate that expression of BIM,...
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| Publicado no: | Pigment Cell Melanoma Res |
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| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2007
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4916913/ https://ncbi.nlm.nih.gov/pubmed/18715233 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1755-148X.2008.00491.x |
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