Hyperleptinemia is associated with impaired pulmonary host defense

We have previously reported that obesity attenuates pulmonary inflammation in both patients with acute respiratory distress syndrome (ARDS) and in mouse models of the disease. We hypothesized that obesity-associated hyperleptinemia, and not body mass per se, drives attenuation of the pulmonary infla...

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Bibliografski detalji
Izdano u:JCI Insight
Glavni autori: Ubags, Niki D.J., Stapleton, Renee D., Vernooy, Juanita H.J., Burg, Elianne, Bement, Jenna, Hayes, Catherine M., Ventrone, Sebastian, Zabeau, Lennart, Tavernier, Jan, Poynter, Matthew E., Parsons, Polly E., Dixon, Anne E., Wargo, Matthew J., Littenberg, Benjamin, Wouters, Emiel F.M., Suratt, Benjamin T.
Format: Artigo
Jezik:Inglês
Izdano: American Society for Clinical Investigation 2016
Teme:
Research Article
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4916854/
https://ncbi.nlm.nih.gov/pubmed/27347561
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.82101
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