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The role of leptin in the development of pulmonary neutrophilia in infection and Acute Lung Injury

OBJECTIVE: One of the hallmarks of severe pneumonia and associated Acute Lung Injury (ALI) is neutrophil recruitment to the lung. Leptin is thought to be up-regulated in the lung following injury and to exert diverse effects on leukocytes, influencing both chemotaxis and survival. We hypothesized th...

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Dades bibliogràfiques
Autors principals: Ubags, Niki D., Vernooy, Juanita H., Burg, Elianne, Hayes, Catherine, Bement, Jenna, Dilli, Estee, Zabeau, Lennart, Abraham, Edward, Poch, Katie R., Nick, Jerry A., Dienz, Oliver, Zuñiga, Joaquin, Wargo, Matthew J., Mizgerd, Joseph P., Tavernier, Jan, Rincón, Mercedes, Poynter, Matthew E., Wouters, Emiel F.M., Suratt, Benjamin T.
Format: Artigo
Idioma:Inglês
Publicat: 2014
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3947045/
https://ncbi.nlm.nih.gov/pubmed/24231757
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/CCM.0000000000000048
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