Hyperleptinemia is associated with impaired pulmonary host defense

We have previously reported that obesity attenuates pulmonary inflammation in both patients with acute respiratory distress syndrome (ARDS) and in mouse models of the disease. We hypothesized that obesity-associated hyperleptinemia, and not body mass per se, drives attenuation of the pulmonary infla...

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Bibliografiska uppgifter
I publikationen:JCI Insight
Huvudupphovsmän: Ubags, Niki D.J., Stapleton, Renee D., Vernooy, Juanita H.J., Burg, Elianne, Bement, Jenna, Hayes, Catherine M., Ventrone, Sebastian, Zabeau, Lennart, Tavernier, Jan, Poynter, Matthew E., Parsons, Polly E., Dixon, Anne E., Wargo, Matthew J., Littenberg, Benjamin, Wouters, Emiel F.M., Suratt, Benjamin T.
Materialtyp: Artigo
Språk:Inglês
Publicerad: American Society for Clinical Investigation 2016
Ämnen:
Research Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4916854/
https://ncbi.nlm.nih.gov/pubmed/27347561
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.82101
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