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Rescue of the Functional Alterations of Motor Cortical Circuits in Arginase Deficiency by Neonatal Gene Therapy

Arginase 1 deficiency is a urea cycle disorder associated with hyperargininemia, spastic diplegia, loss of ambulation, intellectual disability, and seizures. To gain insight on how loss of arginase expression affects the excitability and synaptic connectivity of the cortical neurons in the developin...

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Bibliografiset tiedot
Julkaisussa:J Neurosci
Päätekijät: Cantero, Gloria, Liu, Xiao-Bo, Mervis, Ronald F., Lazaro, Maria T., Cederbaum, Stephen D., Golshani, Peyman, Lipshutz, Gerald S.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Society for Neuroscience 2016
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC4916246/
https://ncbi.nlm.nih.gov/pubmed/27335400
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.0897-16.2016
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