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Optimal marker-strategy clinical trial design to detect predictive markers for targeted therapy
In developing targeted therapy, the marker-strategy design (MSD) provides an important approach to evaluate the predictive marker effect. This design first randomizes patients into non-marker-based or marker-based strategies. Patients allocated to the non-marker-based strategy are then further rando...
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| Vydáno v: | Biostatistics |
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| Hlavní autoři: | , , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
Oxford University Press
2016
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4915612/ https://ncbi.nlm.nih.gov/pubmed/26951724 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/biostatistics/kxw006 |
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