Endothelial Fcγ Receptor IIB Activation Blunts Insulin Delivery to Skeletal Muscle to Cause Insulin Resistance in Mice

Modest elevations in C-reactive protein (CRP) are associated with type 2 diabetes. We previously revealed in mice that increased CRP causes insulin resistance and mice globally deficient in the CRP receptor Fcγ receptor IIB (FcγRIIB) were protected from the disorder. FcγRIIB is expressed in numerous...

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Detalhes bibliográficos
Publicado no:Diabetes
Main Authors: Tanigaki, Keiji, Chambliss, Ken L., Yuhanna, Ivan S., Sacharidou, Anastasia, Ahmed, Mohamed, Atochin, Dmitriy N., Huang, Paul L., Shaul, Philip W., Mineo, Chieko
Formato: Artigo
Idioma:Inglês
Publicado em: American Diabetes Association 2016
Assuntos:
Pathophysiology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4915578/
https://ncbi.nlm.nih.gov/pubmed/27207525
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db15-1605
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