Endothelial Fcγ Receptor IIB Activation Blunts Insulin Delivery to Skeletal Muscle to Cause Insulin Resistance in Mice

Modest elevations in C-reactive protein (CRP) are associated with type 2 diabetes. We previously revealed in mice that increased CRP causes insulin resistance and mice globally deficient in the CRP receptor Fcγ receptor IIB (FcγRIIB) were protected from the disorder. FcγRIIB is expressed in numerous...

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Dades bibliogràfiques
Publicat a:Diabetes
Autors principals: Tanigaki, Keiji, Chambliss, Ken L., Yuhanna, Ivan S., Sacharidou, Anastasia, Ahmed, Mohamed, Atochin, Dmitriy N., Huang, Paul L., Shaul, Philip W., Mineo, Chieko
Format: Artigo
Idioma:Inglês
Publicat: American Diabetes Association 2016
Matèries:
Pathophysiology
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4915578/
https://ncbi.nlm.nih.gov/pubmed/27207525
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db15-1605
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