Deficiency of the oxidative damage-specific DNA glycosylase NEIL1 leads to reduced germinal center B cell expansion

Mammalian cells possess multiple DNA glycosylases, including OGG1, NTH1, NEIL1, NEIL2 and NEIL3, for the repair of oxidative DNA damage. Among these, NEIL1 and NEIL2 are able to excise oxidized bases on single stranded or bubble-structured DNA and has been implicated in repair of oxidative damage as...

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Publicado no:DNA Repair (Amst)
Main Authors: Mori, Hiromi, Ouchida, Rika, Hijikata, Atsushi, Kitamura, Hiroshi, Ohara, Osamu, Li, Yingqian, Gao, Xiang, Yasui, Akira, Lloyd, R. Stephen, Wang, Ji-Yang
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4915481/
https://ncbi.nlm.nih.gov/pubmed/19782007
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.dnarep.2009.08.007
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