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The role of insulin/IGF-1 signaling in the longevity of model invertebrates, C. elegans and D. melanogaster

Insulin/insulin-like growth factor (IGF)-1 signaling (IIS) pathway regulates aging in many organisms, ranging from simple invertebrates to mammals, including humans. Many seminal discoveries regarding the roles of IIS in aging and longevity have been made by using the roundworm Caenorhabditis elegan...

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Detalles Bibliográficos
Publicado en:BMB Rep
Main Authors: Altintas, Ozlem, Park, Sangsoon, Lee, Seung-Jae V.
Formato: Artigo
Idioma:Inglês
Publicado: Korean Society for Biochemistry and Molecular Biology 2016
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4915121/
https://ncbi.nlm.nih.gov/pubmed/26698870
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.5483/BMBRep.2016.49.2.261
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