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Genome-wide placental DNA methylation analysis of severely growth-discordant monochorionic twins reveals novel epigenetic targets for intrauterine growth restriction

BACKGROUND: Intrauterine growth restriction (IUGR), which refers to reduced fetal growth in the context of placental insufficiency, is etiologically heterogeneous. IUGR is associated not only with perinatal morbidity and mortality but also with adult-onset disorders, such as cardiovascular disease a...

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Detalhes bibliográficos
Publicado no:Clin Epigenetics
Main Authors: Roifman, Maian, Choufani, Sanaa, Turinsky, Andrei L., Drewlo, Sascha, Keating, Sarah, Brudno, Michael, Kingdom, John, Weksberg, Rosanna
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4915063/
https://ncbi.nlm.nih.gov/pubmed/27330572
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13148-016-0238-x
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