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Genome-wide placental DNA methylation analysis of severely growth-discordant monochorionic twins reveals novel epigenetic targets for intrauterine growth restriction

BACKGROUND: Intrauterine growth restriction (IUGR), which refers to reduced fetal growth in the context of placental insufficiency, is etiologically heterogeneous. IUGR is associated not only with perinatal morbidity and mortality but also with adult-onset disorders, such as cardiovascular disease a...

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Pubblicato in:Clin Epigenetics
Autori principali: Roifman, Maian, Choufani, Sanaa, Turinsky, Andrei L., Drewlo, Sascha, Keating, Sarah, Brudno, Michael, Kingdom, John, Weksberg, Rosanna
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2016
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4915063/
https://ncbi.nlm.nih.gov/pubmed/27330572
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13148-016-0238-x
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