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Non-homologous end joining repair in Xenopus egg extract
Non-homologous end joining (NHEJ) is a major DNA double-strand break (DSB) repair mechanism. We characterized here a series of plasmid-based DSB templates that were repaired in Xenopus egg extracts via the canonical, Ku-dependent NHEJ pathway. We showed that the template with compatible ends was eff...
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| Published in: | Sci Rep |
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| Main Authors: | , |
| Format: | Artigo |
| Language: | Inglês |
| Published: |
Nature Publishing Group
2016
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4914968/ https://ncbi.nlm.nih.gov/pubmed/27324260 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep27797 |
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