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Small-scale extracts for the study of nucleotide excision repair and non-homologous end joining

The repair of DNA by nucleotide excision repair (NER) and non-homologous end joining (NHEJ) is essential for maintenance of genomic integrity and cell viability. Examination of NHEJ and NER in vitro using cell-free extracts has led to a deeper understanding of the biochemical mechanisms that underli...

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Bibliographic Details
Main Authors: Smeaton, Michael B., Miller, Paul S., Ketner, Gary, Hanakahi, Les A.
Format: Artigo
Language:Inglês
Published: Oxford University Press 2007
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2190712/
https://ncbi.nlm.nih.gov/pubmed/18073193
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkm974
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