Loss of Free Fatty Acid Receptor 2 leads to impaired islet mass and beta cell survival

The regulation of pancreatic β cell mass is a critical factor to help maintain normoglycemia during insulin resistance. Nutrient-sensing G protein-coupled receptors (GPCR) contribute to aspects of β cell function, including regulation of β cell mass. Nutrients such as free fatty acids (FFAs) contrib...

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Udgivet i:Sci Rep
Main Authors: Villa, Stephanie R., Priyadarshini, Medha, Fuller, Miles H., Bhardwaj, Tanya, Brodsky, Michael R., Angueira, Anthony R., Mosser, Rockann E., Carboneau, Bethany A., Tersey, Sarah A., Mancebo, Helena, Gilchrist, Annette, Mirmira, Raghavendra G., Gannon, Maureen, Layden, Brian T.
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2016
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4914960/
https://ncbi.nlm.nih.gov/pubmed/27324831
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep28159
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