Loss of Free Fatty Acid Receptor 2 leads to impaired islet mass and beta cell survival

The regulation of pancreatic β cell mass is a critical factor to help maintain normoglycemia during insulin resistance. Nutrient-sensing G protein-coupled receptors (GPCR) contribute to aspects of β cell function, including regulation of β cell mass. Nutrients such as free fatty acids (FFAs) contrib...

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Publicado no:Sci Rep
Main Authors: Villa, Stephanie R., Priyadarshini, Medha, Fuller, Miles H., Bhardwaj, Tanya, Brodsky, Michael R., Angueira, Anthony R., Mosser, Rockann E., Carboneau, Bethany A., Tersey, Sarah A., Mancebo, Helena, Gilchrist, Annette, Mirmira, Raghavendra G., Gannon, Maureen, Layden, Brian T.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4914960/
https://ncbi.nlm.nih.gov/pubmed/27324831
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep28159
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