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Colistin and Polymyxin B Dosage Regimens against Acinetobacter baumannii: Differences in Activity and the Emergence of Resistance

Infections caused by multidrug-resistant Acinetobacter baumannii are a major public health problem, and polymyxins are often the last line of therapy for recalcitrant infections by such isolates. The pharmacokinetics of the two clinically used polymyxins, polymyxin B and colistin, differ considerabl...

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Bibliographische Detailangaben
Veröffentlicht in:Antimicrob Agents Chemother
Hauptverfasser: Cheah, Soon-Ee, Li, Jian, Tsuji, Brian T., Forrest, Alan, Bulitta, Jürgen B., Nation, Roger L.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2016
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4914682/
https://ncbi.nlm.nih.gov/pubmed/27067324
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.02927-15
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