Synergy between Colistin and the Signal Peptidase Inhibitor MD3 Is Dependent on the Mechanism of Colistin Resistance in Acinetobacter baumannii

Synergy between colistin and the signal peptidase inhibitor MD3 was tested against isogenic mutants and clinical pairs of Acinetobacter baumannii isolates. Checkerboard assays and growth curves showed synergy against both colistin-susceptible strains (fractional inhibitory concentration index [FIC(i...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
में प्रकाशित:Antimicrob Agents Chemother
मुख्य लेखकों: Martínez-Guitián, Marta, Vázquez-Ucha, Juan C., Odingo, Joshua, Parish, Tanya, Poza, Margarita, Waite, Richard D., Bou, German, Wareham, David W., Beceiro, Alejandro
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: American Society for Microbiology 2016
विषय:
Mechanisms of Resistance
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC4914650/
https://ncbi.nlm.nih.gov/pubmed/27139471
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00510-16
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