Combination Chemotherapy with Suboptimal Doses of Benznidazole and Pentoxifylline Sustains Partial Reversion of Experimental Chagas' Heart Disease

Chronic chagasic cardiomyopathy (CCC) progresses with parasite persistence, fibrosis, and electrical alterations associated with an unbalanced immune response such as high plasma levels of tumor necrosis factor (TNF) and nitric oxide (NO). Presently, the available treatments only mitigate the sympto...

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Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Antimicrob Agents Chemother
Päätekijät: Vilar-Pereira, Glaucia, Resende Pereira, Isabela, de Souza Ruivo, Leonardo Alexandre, Cruz Moreira, Otacilio, da Silva, Andrea Alice, Britto, Constança, Lannes-Vieira, Joseli
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: American Society for Microbiology 2016
Aiheet:
Experimental Therapeutics
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC4914640/
https://ncbi.nlm.nih.gov/pubmed/27161638
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.02123-15
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