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Combination Chemotherapy with Suboptimal Doses of Benznidazole and Pentoxifylline Sustains Partial Reversion of Experimental Chagas' Heart Disease

Chronic chagasic cardiomyopathy (CCC) progresses with parasite persistence, fibrosis, and electrical alterations associated with an unbalanced immune response such as high plasma levels of tumor necrosis factor (TNF) and nitric oxide (NO). Presently, the available treatments only mitigate the sympto...

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Vydáno v:Antimicrob Agents Chemother
Hlavní autoři: Vilar-Pereira, Glaucia, Resende Pereira, Isabela, de Souza Ruivo, Leonardo Alexandre, Cruz Moreira, Otacilio, da Silva, Andrea Alice, Britto, Constança, Lannes-Vieira, Joseli
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2016
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4914640/
https://ncbi.nlm.nih.gov/pubmed/27161638
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.02123-15
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