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Combination Chemotherapy with Suboptimal Doses of Benznidazole and Pentoxifylline Sustains Partial Reversion of Experimental Chagas' Heart Disease
Chronic chagasic cardiomyopathy (CCC) progresses with parasite persistence, fibrosis, and electrical alterations associated with an unbalanced immune response such as high plasma levels of tumor necrosis factor (TNF) and nitric oxide (NO). Presently, the available treatments only mitigate the sympto...
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Vydáno v: | Antimicrob Agents Chemother |
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Hlavní autoři: | , , , , , , |
Médium: | Artigo |
Jazyk: | Inglês |
Vydáno: |
American Society for Microbiology
2016
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Témata: | |
On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4914640/ https://ncbi.nlm.nih.gov/pubmed/27161638 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.02123-15 |
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