Ioncopy: a novel method for calling copy number alterations in amplicon sequencing data including significance assessment

Recently, it has been demonstrated that calling of copy number alterations (CNAs) from amplicon sequencing (AS) data is feasible. Most approaches, however, require non-tumor (germline) DNA for data normalization. Here, we present the method Ioncopy for CNA detection which requires no normal controls...

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Enregistré dans:
Détails bibliographiques
Publié dans:Oncotarget
Auteurs principaux: Budczies, Jan, Pfarr, Nicole, Stenzinger, Albrecht, Treue, Denise, Endris, Volker, Ismaeel, Fakher, Bangemann, Nikola, Blohmer, Jens-Uwe, Dietel, Manfred, Loibl, Sibylle, Klauschen, Frederick, Weichert, Wilko, Denkert, Carsten
Format: Artigo
Langue:Inglês
Publié: Impact Journals LLC 2016
Sujets:
Clinical Research Paper
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4914355/
https://ncbi.nlm.nih.gov/pubmed/26910888
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.7451
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