Ioncopy: a novel method for calling copy number alterations in amplicon sequencing data including significance assessment

Recently, it has been demonstrated that calling of copy number alterations (CNAs) from amplicon sequencing (AS) data is feasible. Most approaches, however, require non-tumor (germline) DNA for data normalization. Here, we present the method Ioncopy for CNA detection which requires no normal controls...

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Vydáno v:Oncotarget
Hlavní autoři: Budczies, Jan, Pfarr, Nicole, Stenzinger, Albrecht, Treue, Denise, Endris, Volker, Ismaeel, Fakher, Bangemann, Nikola, Blohmer, Jens-Uwe, Dietel, Manfred, Loibl, Sibylle, Klauschen, Frederick, Weichert, Wilko, Denkert, Carsten
Médium: Artigo
Jazyk:Inglês
Vydáno: Impact Journals LLC 2016
Témata:
Clinical Research Paper
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4914355/
https://ncbi.nlm.nih.gov/pubmed/26910888
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.7451
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