Ioncopy: a novel method for calling copy number alterations in amplicon sequencing data including significance assessment

Recently, it has been demonstrated that calling of copy number alterations (CNAs) from amplicon sequencing (AS) data is feasible. Most approaches, however, require non-tumor (germline) DNA for data normalization. Here, we present the method Ioncopy for CNA detection which requires no normal controls...

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Detalles Bibliográficos
Publicado en:Oncotarget
Autores principales: Budczies, Jan, Pfarr, Nicole, Stenzinger, Albrecht, Treue, Denise, Endris, Volker, Ismaeel, Fakher, Bangemann, Nikola, Blohmer, Jens-Uwe, Dietel, Manfred, Loibl, Sibylle, Klauschen, Frederick, Weichert, Wilko, Denkert, Carsten
Formato: Artigo
Lenguaje:Inglês
Publicado: Impact Journals LLC 2016
Materias:
Clinical Research Paper
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4914355/
https://ncbi.nlm.nih.gov/pubmed/26910888
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.7451
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