Ioncopy: a novel method for calling copy number alterations in amplicon sequencing data including significance assessment

Recently, it has been demonstrated that calling of copy number alterations (CNAs) from amplicon sequencing (AS) data is feasible. Most approaches, however, require non-tumor (germline) DNA for data normalization. Here, we present the method Ioncopy for CNA detection which requires no normal controls...

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Detaylı Bibliyografya
Yayımlandı:Oncotarget
Asıl Yazarlar: Budczies, Jan, Pfarr, Nicole, Stenzinger, Albrecht, Treue, Denise, Endris, Volker, Ismaeel, Fakher, Bangemann, Nikola, Blohmer, Jens-Uwe, Dietel, Manfred, Loibl, Sibylle, Klauschen, Frederick, Weichert, Wilko, Denkert, Carsten
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Impact Journals LLC 2016
Konular:
Clinical Research Paper
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4914355/
https://ncbi.nlm.nih.gov/pubmed/26910888
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.7451
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