Ioncopy: a novel method for calling copy number alterations in amplicon sequencing data including significance assessment

Recently, it has been demonstrated that calling of copy number alterations (CNAs) from amplicon sequencing (AS) data is feasible. Most approaches, however, require non-tumor (germline) DNA for data normalization. Here, we present the method Ioncopy for CNA detection which requires no normal controls...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Budczies, Jan, Pfarr, Nicole, Stenzinger, Albrecht, Treue, Denise, Endris, Volker, Ismaeel, Fakher, Bangemann, Nikola, Blohmer, Jens-Uwe, Dietel, Manfred, Loibl, Sibylle, Klauschen, Frederick, Weichert, Wilko, Denkert, Carsten
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2016
Assuntos:
Clinical Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4914355/
https://ncbi.nlm.nih.gov/pubmed/26910888
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.7451
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