A novel small molecule STAT3 inhibitor, LY5, inhibits cell viability, colony formation, and migration of colon and liver cancer cells

Signal Transducer and Activator of Transcription 3 (STAT3) is persistently activated in human liver and colon cancer cells and is required for cancer cell viability, survival and migration. Therefore, inhibition of STAT3 signaling may be a viable therapeutic approach for these two cancers. We recent...

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Vydáno v:Oncotarget
Hlavní autoři: Zhao, Chongqiang, Wang, Wenlong, Yu, Wenying, Jou, David, Wang, Yina, Ma, Haiyan, Xiao, Hui, Qin, Hua, Zhang, Cuntai, Lü, Jiagao, Li, Sheng, Li, Chenglong, Lin, Jiayuh, Lin, Li
Médium: Artigo
Jazyk:Inglês
Vydáno: Impact Journals LLC 2016
Témata:
Research Paper
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4914331/
https://ncbi.nlm.nih.gov/pubmed/26883202
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.7338
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