Growth-suppressive activity of raloxifene on liver cancer cells by targeting IL-6/GP130 signaling

BACKGROUND: Interleukin-6 (IL-6) is a multifunctional cytokine, which is involved in the regulation of differentiation and growth of certain types of tumor cells. Constitutive activation of Signal Transducer and Activator of Transcription 3 (STAT3) induced by IL-6 is frequently detected in liver can...

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Udgivet i:Oncotarget
Main Authors: Wang, Yina, Ma, Haiyan, Zhao, Chongqiang, Liu, Tianshu, Yan, Dan, Jou, David, Li, Huameng, Zhang, Cuntai, Lü, Jiagao, Li, Chenglong, Lin, Jiayuh, Li, Sheng, Lin, Li
Format: Artigo
Sprog:Inglês
Udgivet: Impact Journals LLC 2017
Fag:
Research Paper
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5464902/
https://ncbi.nlm.nih.gov/pubmed/28430601
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.16898
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