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Bazedoxifene as a novel GP130 inhibitor for Colon Cancer therapy

BACKGROUND: Interleukin-11 (IL-11), a dominant IL-6 family cytokine, is involved in tumorigenesis, tumor progression and differentiation in colon cancer cells. IL-11 signaling has been recently identified as a potential therapeutic target in colon cancer. Bazedoxifene, a third- generation selective...

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Podrobná bibliografie
Vydáno v:J Exp Clin Cancer Res
Hlavní autoři: Wei, Jia, Ma, Ling, Lai, Yi-Hui, Zhang, Ruijie, Li, Huameng, Li, Chenglong, Lin, Jiayuh
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2019
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6368818/
https://ncbi.nlm.nih.gov/pubmed/30736824
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13046-019-1072-8
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