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Accelerated geroncogenesis in hereditary breast-ovarian cancer syndrome
The geroncogenesis hypothesis postulates that the decline in metabolic cellular health that occurs naturally with aging drives a “field effect” predisposing normal tissues for cancer development. We propose that mutations in the cancer susceptibility genes BRCA1/2 might trigger “accelerated geroncog...
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| Publié dans: | Oncotarget |
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| Auteurs principaux: | , , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Impact Journals LLC
2016
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4914261/ https://ncbi.nlm.nih.gov/pubmed/26943589 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.7867 |
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