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Metformin targets histone acetylation in cancer-prone epithelial cells

The usage of metabolic intermediates as substrates for chromatin-modifying enzymes provides a direct link between the metabolic state of the cell and epigenetics. Because this metabolism-epigenetics axis can regulate not only normal but also diseased states, it is reasonable to suggest that manipula...

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Detalhes bibliográficos
Publicado no:Cell Cycle
Main Authors: Cuyàs, Elisabet, Fernández-Arroyo, Salvador, Joven, Jorge, Menendez, Javier A.
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5224457/
https://ncbi.nlm.nih.gov/pubmed/27792453
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15384101.2016.1249547
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