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Metformin inhibits RANKL and sensitizes cancer stem cells to denosumab
The increased propensity of BRCA1 mutation carriers to develop aggressive breast tumors with stem-like properties begins to be understood in terms of osteoprotegerin (OPG)-unrestricted cross-talk between RANKL-overproducing progesterone-sensor cells and cancer-initiating RANK(+) responder cells that...
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| Publicado no: | Cell Cycle |
|---|---|
| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Taylor & Francis
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5499830/ https://ncbi.nlm.nih.gov/pubmed/28387573 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15384101.2017.1310353 |
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