Anti-protozoal and anti-bacterial antibiotics that inhibit protein synthesis kill cancer subtypes enriched for stem cell-like properties

Key players in translational regulation such as ribosomes might represent powerful, but hitherto largely unexplored, targets to eliminate drug-refractory cancer stem cells (CSCs). A recent study by the Lisanti group has documented how puromycin, an old antibiotic derived from Streptomyces alboniger...

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Detalhes bibliográficos
Publicado no:Cell Cycle
Main Authors: Cuyàs, Elisabet, Martin-Castillo, Begoña, Corominas-Faja, Bruna, Massaguer, Anna, Bosch-Barrera, Joaquim, Menendez, Javier A
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4825717/
https://ncbi.nlm.nih.gov/pubmed/25970790
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15384101.2015.1044173
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