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Cre-dependent DNA recombination activates a STING-dependent innate immune response
Gene-recombinase technologies, such as Cre/loxP-mediated DNA recombination, are important tools in the study of gene function, but have potential side effects due to damaging activity on DNA. Here we show that DNA recombination by Cre instigates a robust antiviral response in mammalian cells, indepe...
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| 出版年: | Nucleic Acids Res |
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| 主要な著者: | , , , , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Oxford University Press
2016
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4914124/ https://ncbi.nlm.nih.gov/pubmed/27166376 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkw405 |
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