Cortical Dopamine Transmission as Measured with the [(11)C]FLB 457 – Amphetamine PET Imaging Paradigm Is Not Influenced by COMT Genotype

Basic investigations link a Val158Met polymorphism (rs4680) in the catechol-O-methyltransferase (COMT) gene to not only its enzymatic activity, but also to its dopaminergic tone in the prefrontal cortex. Previous PET studies have documented the relationship between COMT Val158Met polymorphism and D(...

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Detaylı Bibliyografya
Yayımlandı:PLoS One
Asıl Yazarlar: Narendran, Rajesh, Tumuluru, Divya, May, Maureen A., Chowdari, Kodavali V., Himes, Michael L., Fasenmyer, Kelli, Frankle, W. Gordon, Nimgaonkar, Vishwajit L.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Public Library of Science 2016
Konular:
Research Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4913897/
https://ncbi.nlm.nih.gov/pubmed/27322568
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0157867
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