Evaluation of dopamine D(2/3) specific binding in the cerebellum for the PET radiotracer [(11)C]FLB 457: implications for measuring cortical dopamine release

In a recent PET study we demonstrated the ability to measure amphetamine-induced DA release in the human cortex with the dopamine D(2/3) radioligand [(11)C]FLB 457. As previous studies in animals have shown that a relatively high fraction of the [(11)C]FLB 457 signal in the cerebellum represents spe...

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Hauptverfasser: Narendran, Rajesh, Mason, N. Scott, Chen, Chi-Min, Himes, Michael, Keating, Patrick, May, Maureen A., Rabiner, Eugenii A., Laruelle, Marc, Mathis, Chester A., Frankle, W. Gordon
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2011
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3135684/
https://ncbi.nlm.nih.gov/pubmed/21360596
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/syn.20926
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