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Promoter CpG Island Methylation of Genes in Key Cancer Pathways Associates with Clinical Outcome in High Grade Serous Ovarian Cancer

PURPOSE: We aimed to identify DNA methylation biomarkers of progression free survival (PFS) to platinum-based chemotherapy in high grade serous ovarian cancer (HGSOC) within biologically relevant ovarian cancer associated pathways. EXPERIMENTAL DESIGN: Association with PFS of CpG island (CGI) promot...

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Détails bibliographiques
Publié dans:Clin Cancer Res
Auteurs principaux: Dai, Wei, Zeller, Constanze, Masrour, Nahal, Siddiqui, Nadeem, Paul, James, Brown, Robert
Format: Artigo
Langue:Inglês
Publié: 2013
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4913863/
https://ncbi.nlm.nih.gov/pubmed/23965899
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-13-1217
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