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Connexin 50 Regulates Surface Ball-and-Socket Structures and Fiber Cell Organization

PURPOSE: The roles of gap junction protein connexin 50 (Cx50) encoded by Gja8, during lens development are not fully understood. Connexin 50 knockout (KO) lenses have decreased proliferation of epithelial cells and altered fiber cell denucleation. We further investigated the mechanism for cellular d...

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Detalhes bibliográficos
Publicado no:Invest Ophthalmol Vis Sci
Main Authors: Wang, Eddie, Geng, Andrew, Maniar, Ankur M., Mui, Byron W. H., Gong, Xiaohua
Formato: Artigo
Idioma:Inglês
Publicado em: The Association for Research in Vision and Ophthalmology 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4913802/
https://ncbi.nlm.nih.gov/pubmed/27281269
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1167/iovs.16-19521
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