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Connexin 50-R205G Mutation Perturbs Lens Epithelial Cell Proliferation and Differentiation

PURPOSE: To investigate the underlying mechanisms for how the mouse Cx50-R205G point mutation, a homologue of the human Cx50-R198W mutation that is linked to cataract-microcornea syndrome, affects proper lens growth and fiber cell differentiation to lead to severe lens phenotypes. METHODS: EdU label...

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Detalhes bibliográficos
Publicado no:Invest Ophthalmol Vis Sci
Main Authors: Tjahjono, Nikki, Xia, Chun-hong, Li, Rachel, Chu, Sarah, Wang, Jessica, Gong, Xiaohua
Formato: Artigo
Idioma:Inglês
Publicado em: The Association for Research in Vision and Ophthalmology 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7401428/
https://ncbi.nlm.nih.gov/pubmed/32182330
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1167/iovs.61.3.25
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