Pro-inflammatory self-reactive T cells are found within TCR-αβ(+)CD4(−)CD8(−)PD-1(+) cells in normal mice

TCR-αβ(+) DN T cells (CD3(+) TCR-αβ(+) CD4(−) CD8(−) NK1.1(−) CD49b(−)) represent a minor heterogeneous population in healthy mice and humans. Both pro-inflammatory and regulatory capacities have been attributed to these cells which are expanded in several autoimmune diseases. Importantly, previous...

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Bibliografiska uppgifter
I publikationen:Eur J Immunol
Huvudupphovsmän: Rodríguez-Rodríguez, Noé, Apostolidis, Sokratis A., Fitzgerald, Lauren, Meehan, Bronwyn S., Corbett, Alexandra J., Manuel Martín-Villa, José, McCluskey, James, Tsokos, George C., Crispín, José C.
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2016
Ämnen:
Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4913481/
https://ncbi.nlm.nih.gov/pubmed/27060346
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/eji.201546056
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