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Human TCR-αβ(+) CD4(−) CD8(−) T Cells Can Derive from CD8(+) T Cells and Display an Inflammatory Effector Phenotype
The origin and function of human double negative (DN) TCR-αβ(+) T cells is unknown. They are thought to contribute to the pathogenesis of systemic lupus erythematosus because they expand and accumulate in inflamed organs. In this study, we provide evidence that human TCR-αβ(+) CD4(−) CD8(−) DN T cel...
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| Main Authors: | , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2009
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2878279/ https://ncbi.nlm.nih.gov/pubmed/19734235 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.0901533 |
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