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Programmed cell death 1 and Helios distinguish TCR-αβ(+) double negative (CD4(-)CD8(-)) T cells that derive from self-reactive CD8 T cells()

TCR-αβ(+) double negative (DN; CD4(-)CD8(-)) T cells represent a poorly understood cellular subset suggested to contribute to the pathogenesis of the autoimmune disease systemic lupus erythematosus. DN T cells have been proposed to derive from CD8(+) cells. However, the conditions that govern the lo...

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Detalhes bibliográficos
Publicado no:J Immunol
Main Authors: Rodríguez-Rodríguez, Noé, Apostolidis, Sokratis A., Penaloza-MacMaster, Pablo, Manuel Martín Villa, José, Barouch, Dan H., Tsokos, George C., Crispín, José C.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4503929/
https://ncbi.nlm.nih.gov/pubmed/25825451
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1402775
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