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The intestinal microbiome, barrier function, and immune system in inflammatory bowel disease: a tripartite pathophysiological circuit with implications for new therapeutic directions

We discuss the tripartite pathophysiological circuit of inflammatory bowel disease (IBD), involving the intestinal microbiota, barrier function, and immune system. Dysfunction in each of these physiological components (dysbiosis, leaky gut, and inflammation) contributes in a mutually interdependent...

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Podrobná bibliografie
Vydáno v:Therap Adv Gastroenterol
Hlavní autoři: Vindigni, Stephen M., Zisman, Timothy L., Suskind, David L., Damman, Christopher J.
Médium: Artigo
Jazyk:Inglês
Vydáno: SAGE Publications 2016
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4913337/
https://ncbi.nlm.nih.gov/pubmed/27366227
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/1756283X16644242
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