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The intestinal microbiome, barrier function, and immune system in inflammatory bowel disease: a tripartite pathophysiological circuit with implications for new therapeutic directions

We discuss the tripartite pathophysiological circuit of inflammatory bowel disease (IBD), involving the intestinal microbiota, barrier function, and immune system. Dysfunction in each of these physiological components (dysbiosis, leaky gut, and inflammation) contributes in a mutually interdependent...

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Publicat a:Therap Adv Gastroenterol
Autors principals: Vindigni, Stephen M., Zisman, Timothy L., Suskind, David L., Damman, Christopher J.
Format: Artigo
Idioma:Inglês
Publicat: SAGE Publications 2016
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4913337/
https://ncbi.nlm.nih.gov/pubmed/27366227
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/1756283X16644242
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