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The intestinal microbiome, barrier function, and immune system in inflammatory bowel disease: a tripartite pathophysiological circuit with implications for new therapeutic directions

We discuss the tripartite pathophysiological circuit of inflammatory bowel disease (IBD), involving the intestinal microbiota, barrier function, and immune system. Dysfunction in each of these physiological components (dysbiosis, leaky gut, and inflammation) contributes in a mutually interdependent...

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Detalhes bibliográficos
Publicado no:Therap Adv Gastroenterol
Main Authors: Vindigni, Stephen M., Zisman, Timothy L., Suskind, David L., Damman, Christopher J.
Formato: Artigo
Idioma:Inglês
Publicado em: SAGE Publications 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4913337/
https://ncbi.nlm.nih.gov/pubmed/27366227
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/1756283X16644242
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