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The intestinal microbiome, barrier function, and immune system in inflammatory bowel disease: a tripartite pathophysiological circuit with implications for new therapeutic directions

We discuss the tripartite pathophysiological circuit of inflammatory bowel disease (IBD), involving the intestinal microbiota, barrier function, and immune system. Dysfunction in each of these physiological components (dysbiosis, leaky gut, and inflammation) contributes in a mutually interdependent...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Therap Adv Gastroenterol
Prif Awduron: Vindigni, Stephen M., Zisman, Timothy L., Suskind, David L., Damman, Christopher J.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: SAGE Publications 2016
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4913337/
https://ncbi.nlm.nih.gov/pubmed/27366227
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/1756283X16644242
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