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Mongersen, an oral Smad7 antisense oligonucleotide, in patients with active Crohn’s disease
In Crohn’s disease (CD), the tissue-damaging inflammation is sustained by defects of counter-regulatory mechanisms, which normally inhibit immune-inflammatory signals and promote repair of mucosal injury. In particular, in inflamed gut of CD patients there are elevated levels of Smad7, an intracellu...
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| Pubblicato in: | Therap Adv Gastroenterol |
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| Autori principali: | , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
SAGE Publications
2016
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4913329/ https://ncbi.nlm.nih.gov/pubmed/27366221 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/1756283X16636781 |
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