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Mongersen, an oral Smad7 antisense oligonucleotide, in patients with active Crohn’s disease

In Crohn’s disease (CD), the tissue-damaging inflammation is sustained by defects of counter-regulatory mechanisms, which normally inhibit immune-inflammatory signals and promote repair of mucosal injury. In particular, in inflamed gut of CD patients there are elevated levels of Smad7, an intracellu...

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Bibliografiske detaljer
Udgivet i:Therap Adv Gastroenterol
Main Authors: Ardizzone, Sandro, Bevivino, Gerolamo, Monteleone, Giovanni
Format: Artigo
Sprog:Inglês
Udgivet: SAGE Publications 2016
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4913329/
https://ncbi.nlm.nih.gov/pubmed/27366221
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/1756283X16636781
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