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Maytansinoid immunoconjugate IMGN901 is cytotoxic in a three-dimensional culture model of multiple myeloma

Environmental-mediated drug-resistance (EM-DR) presents a major challenge for therapeutic development. Tissue microenvironment in the form of extracellular matrix, soluble factors, and stroma contribute to EM-DR. In multiple myeloma (MM), drug-resistance has hindered treatment success with 5-year su...

詳細記述

保存先:
書誌詳細
出版年:Am J Blood Res
主要な著者: Nierste, Brittany A, Gunn, Ellen J, Whiteman, Kathleen R, Lutz, Robert J, Kirshner, Julia
フォーマット: Artigo
言語:Inglês
出版事項: e-Century Publishing Corporation 2016
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4913235/
https://ncbi.nlm.nih.gov/pubmed/27335686
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