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Structural characterization of the maytansinoid–monoclonal antibody immunoconjugate, huN901–DM1, by mass spectrometry
Immunoconjugates are being explored as novel cancer therapies with the promise of target-specific drug delivery. The immunoconjugate, huN901–DM1, composed of the humanized monoclonal IgG(1) antibody, huN901, and the maytansinoid drug, DM1, is being tested in clinical trials to treat small cell lung...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Cold Spring Harbor Laboratory Press
2005
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2253466/ https://ncbi.nlm.nih.gov/pubmed/16081651 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1110/ps.051478705 |
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