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STAT2 is required for TLR-induced murine dendritic cell activation and cross-presentation
TLR stimulated-cross-presentation by conventional dendritic cells (cDCs) is important in host defense and anti-tumor immunity. We recently reported that cDCs lacking the type I interferon (IFN) signaling molecule STAT2 are impaired in cross-presenting tumor antigens to CD8(+)T cells. To investigate...
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| Опубликовано в: : | J Immunol |
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| Главные авторы: | , , , , , , , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
2016
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4912940/ https://ncbi.nlm.nih.gov/pubmed/27233962 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1500152 |
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