STAT2 is required for TLR-induced murine dendritic cell activation and cross-presentation

TLR stimulated-cross-presentation by conventional dendritic cells (cDCs) is important in host defense and anti-tumor immunity. We recently reported that cDCs lacking the type I interferon (IFN) signaling molecule STAT2 are impaired in cross-presenting tumor antigens to CD8(+)T cells. To investigate...

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Bibliografiska uppgifter
I publikationen:J Immunol
Huvudupphovsmän: Xu, Jun, Lee, Michael H., Chakhtoura, Marita, Green, Benjamin L., Kotredes, Kevin P., Chain, Robert W., Sriram, Uma, Gamero, Ana M., Gallucci, Stefania
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2016
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Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4912940/
https://ncbi.nlm.nih.gov/pubmed/27233962
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1500152
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