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CSF-1R–dependent lethal hepatotoxicity when agonistic CD40 antibody given before but not after chemotherapy
Cancer immunotherapies are increasingly effective in the clinic, especially immune checkpoint blockade delivered to patients who have T cell-infiltrated tumors. Agonistic CD40 mAb promotes stromal degradation, and in combination with chemotherapy, drives T cell infiltration and de novo responses aga...
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| Publicado en: | J Immunol |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2016
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4912938/ https://ncbi.nlm.nih.gov/pubmed/27217585 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1600146 |
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