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Redundant G(s)-coupled serotonin receptors regulate amyloid-β metabolism in vivo
BACKGROUND: The aggregation of amyloid-β (Aβ) into insoluble plaques is a hallmark pathology of Alzheimer’s disease (AD). Previous work has shown increasing serotonin levels with selective serotonin re-uptake inhibitor (SSRI) compounds reduces Aβ in the brain interstitial fluid (ISF) in a mouse mode...
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| Publicado en: | Mol Neurodegener |
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| Autores principales: | , , , , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
BioMed Central
2016
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4912779/ https://ncbi.nlm.nih.gov/pubmed/27315796 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13024-016-0112-5 |
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